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Ulcerative colitis (UC) is a chronic inflammatory bowel disease that primarily affects the colon and rectum, causing symptoms such as abdominal pain, diarrhea, rectal bleeding, and urgency. It results from an inappropriate immune response where the body’s immune system mistakenly attacks the lining of the colon, leading to persistent inflammation and ulceration.
Overactivation of JAK pathway leads to increased immune cell activity and inflammation in the colon. JAK inhibitors help reduce this inflammation by blocking specific JAK enzymes involved in the signaling.
If left untreated, ulcerative colitis can lead to severe symptoms, colon damage, increased colorectal cancer risk, and life-threatening complications like toxic megacolon, significantly affecting health and quality of life.
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Upadacitinib for Ulcerative Colitis
Clinical research has shown that Upadacitinib can help individuals with ulcerative colitis achieve remission as early as 8 weeks and maintain it through 1 year.[/vc_column_text]
Faster Symptom Relief
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Faster symptom relief at 2 week
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Faster symptom relief at at 8 weeks
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Long Lasting Steroid Free Remission 1 Year
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among those who achieved remission at 8 weeks
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Visible Colon Lining Repair
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Visible Colon Lining Repair at 8 weeks
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Visible Colon Lining Repair at 12 weeks
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